Stand Februar 2006
Tumor / Region | Tumormarker | Empfohlene Markerkombination |
Tumoren der Atemwege | ||
HNO-Tumoren | SCCA, CEA, CYFRA 21-1, (EBV) | SCCA, CEA |
Bronchial-Ca | ||
- Plattenepithel-Ca | CYFRA 21-1, CEA, TPA, SCCA, | |
- Adeno-Ca | CEA, CYFRA 21-1 | |
- Kleinzelliges Ca | CYFRA 21-1, NSE, CEA, ACTH | |
Gastrointestinale Tumoren | ||
Ösophagus-Ca | CYFRA 21-1, SCCA, CEA, CA 19-9, CA 50 | CEA, SCCA |
Magen-Ca | CA 72-4, CEA, CA 19-9, TPA, CA 50, (Gastrin) | CA 72-4, CEA |
Pankreas | CA 19-9, CEA, TPA | |
- Adeno-Ca | CA 19-9, CEA, CA 125, CA 72-4, TPA | |
- Gastrinom | Gastrin | |
- Insulinom | C-Peptid, Insulin | |
- Glucagonom | Glucagon | |
Leber/Galle | AFP, CEA, CA 19-9 | |
- Leberzell-Ca | AFP, CEA, CA 19-9, HCV, HBV; Metastasen: CEA | |
- Gallengangs-Ca | CA 19-9, CEA, CA125, CA 50 | CEA, CA 19-9 |
Anal-Ca | SCC, CEA | SCC, CEA |
Gynäkologische Tumoren | ||
Mamma-Ca | CA 15-3, CEA, TPA, CA125, CASA, CA54-9 | CA 15-3, CEA, TPA |
Ovarial-Ca | CA 125, CA 72-4 CA 15-3, CEA, CASA | CA125, CA 72-4, CASA |
Uterus | CA125, SCCA, | |
- Cervix-Ca | SCCA, HPV | |
- Korpus-Ca | CA125, CEA, CA 19-9 | |
Blasenmole, Chorion-Ca | ß-HCG | ß-HCG |
Urologische / andrologische Tumoren | ||
Nieren-Ca | TPA, CEA, M2 PK, Erythropoetin, NSE, Renin, Ferritin, Neopterin, | TPA, M2 PK, CEA |
Harnblasen-Ca | TPA, NMP 22, CYFRA21-1, SCCA, CEA | TPA, NMP 22 |
Hoden-Tu | AFP, ß-HCG, PLAP, NSE | AFP, ß-HCG, PLAP |
Prostata-Ca | PSA, freies PSA, PAP, CEA, TPA | PSA, freies PSA |
Keimzelltumoren | AFP, ß-HCG | AFP, ß-HCG |
Tumoren des endokrinen Systems | ||
Hypophysen-Tumoren | Prolaktin, ACTH, HGH, Cortisol, LH, FSH, TSH | Prolaktin, ACTH, HGH, |
Schilddrüsen-Ca | ||
- papillär/follikulär | Thyreoglobulin (HTG), CEA, TPA | HTG, CEA, TPA |
- medullär | Calcitonin, CEA, NSE, Gastrin-Stimulationstest | Calcitonin, CEA |
Nebenschilddrüsen-Ca | PTH | |
NNR-Tumoren | Cortisol, DHEAS, Cortisol-Tagesprofil, Dexamethasontest | Cortisol, DHEAS |
Phäochromozytom | Adrenalin, Noradrenalin, Chromogranin A (= Cg A) NSE, VMS, HVS | Cg A, Katecholamine |
Neuroendokrine Tumoren, Apudome, MEN | Cg A, NSE, Dopa, | |
Karzinoid | 5-HIES, Serotonin, Cg A, NSE | 5-HIES, Cg A |
Neuroblastom | VMS, HVS, LDH, Cg A, NSE, Dopamin, | VMS, HVS, LDH, |
Verschiedene Tumoren | ||
Melanom | Protein S-100, 5-S-Cysteinyl-DOPA | Protein S-100 |
Osteosarkom | Ostase, Hydroxyprolin, TPA, CEA | |
Knochenmetastasen | Ostase, SP, Desoxypyridinolon, Pyridinolon, ICTP, PINP, Marker des Primär-Tu. | |
Malignome des lymphatischen und myeloischen Systems- | TK, ß-2-Mikroglobulin, monokl. Immunglobuline Bence-Jones-Paraproteine Vit B12, Lysozym, Neopterin, LDH, Ferritin, FACS-Analyse | TK, ß-2-MG |